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Medicinal Chemistry 2020

About Conference


Conference Series LLC Ltd invites all the chemical professionals, researchers, professors, scientific communities, delegates, students, business professionals and executives from all over the world to attend the “23nd International Conference on Medicinal Chemistry & Drug Design” which is to be held during August 17-18, 2020 at London,UK which includes prompt Keynote presentations, Oral talks, Poster presentations, Workshops and Exhibitions.

Medicinal Chemistry 2020 is an event intended to provide an exclusive platform to discuss and learn about Medicinal Chemistry, Drug Delivery and Drug Discovery. This event brings together the top professionals in the Medicinal chemistry and Drug Delivery field along with the highly affiliated professors to explore the advancements and latest applications achieved in the field of Pharmaceutical Sciences,  Drug Development, CADD and Drug Delivery, Novel Drug Discovery and Drug Delivery ,Bioorganic and Medicinal Chemistry, Pharmacology and toxicology, Anticancer agents, Analytical Chemistry, Pharmaceutical Industry, Organic Chemistry, Clinical Pharmacology,  Evolution of Organic and Medicinal Chemistry in Pharmaceutical Science, Latest Developments in Alzheimer’s Drugs, Organic and Medicinal Chemistry Technologies for Drug Discovery, Receptors and Inhibitors, Applications of Organic and Medicinal Chemistry in Drug Discovery and Anti Parkinson's Drugs.

Conference Series LLC LTD aims to provide a forum for international researchers from various areas of chemistry, pharmacy, Medicinal Chemistry and Drug Design  to share latest cutting-edge research findings and results about all aspects of Medicinal Chemistry. Each session of the meeting will be included with expert lectures, poster and discussions in the field of Medicinal Chemistry, Pharmaceutical Sciences, Drug Delivery and Drug Development, Pharmaceutical Chemistry and overall applications.

Details of Medicinal Chemistry 2020:

ConferenceSeries.com organizing Medicinal Chemistry Conference in 2019 in Singapore. We organize Medicinal Chemistry Meetings in the fields related to it like Synthetic Organic Chemistry and Pharmacology.

Conference Name

Place

Date

Medicinal Chemistry 2020

London, UK

August 16-17, 2020

Target Audience for Medicinal Chemistry 2020:

Eminent Scientists/ Research Professors in the field of Medicinal chemistry and Drug Delivery, Junior/Senior research fellows, Students, Directors of Pharmaceutical research companies, Chemical Engineers, Members of different physics and Chemistry associations.

 

Sessions and Tracks

 

Track 1:Medicinal Chemistry and Drug Delivery

Medicinal chemistry-based plans are essentially aimed at the chemical modification of low molecular weight drugs in order to increase their lipophilicity or the intention of proper pro-drugs, although this assessment will concentration mainly on the use of pro-drugs and not analog development. Recently, interest has been concentrated on the design and evaluation of pro-drugs that are capable of misusing one or more of the many endogenous transport systems at the level of the blood brain barrier (BBB). The scientific plans are mostly non-invasive approaches of drug transferal to malignancies of the central nervous system (CNS) and are founded on the use of Nano systems (colloidal carriers) such as liposomes, polymeric nanoparticles, solid lipid nanoparticles, polymeric micelles and dendrimers. The bio distribution of these Nano carriers can be manipulated by modifying their surface physico-chemical properties or by coating them with surfactants and polyethylene-glycols (PEGs). Liposomes, surfactant covered polymeric nanoparticles, and solid lipid nanoparticles are promising systems for transfer of drugs to tumors of the CNS. This mini journal discusses issues concerning the scope and limitations of both the medicinal chemistry and scientific approaches. Based on the current findings, it can be concluded that crossing of the BBB and drug transfer to CNS is very multifarious and requires a multidisciplinary approach such as a next to collaboration and collective efforts among researchers of several scientific areas, mainly medicinal chemists, biologists and pharmaceutical technicians.

  • Track 1-1Target discovery and validation
  • Track 1-2Molecular modeling
  • Track 1-3Advances in medicinal chemistry
  • Track 1-4Drug receptor interactions
  • Track 1-5Toxicity, and therapeutic applications of antibiotics, antifungals, and antiviral
  • Track 1-6 Chemotherapeutic Agents

Track 2:Structure-based drug design, virtual screening

 

  • Structure-based drug design, virtual screening starts with processing the 3D target structural information of interest. The target structure may be derived from experimental data (X-ray, NMR or neutron scattering spectroscopy), homology modeling, or from Molecular Dynamics (MD) simulations. There are numerous fundamental issues that should be examined when considering a biological target for SBVS; for example, the drug ability of the receptor, the choice of binding site, the selection of the most relevant protein structure, incorporating receptor flexibility, suitable assignment of protonation states, and consideration of water molecules in a binding site, to name a few. In fact, the identification of ligand binding sites on biological targets is becoming increasingly important. The need for novel modulators of protein/gene function has recently directed the scientific community to pursue drug gable allosteric binding pockets. Another consideration for SBVS includes the careful choice of the compound library to be screened in the VS exercise according to the target in question, and the preprocessing of libraries in order to assign the proper stereochemistry, tautomeric, and protonation states.
  • Track 2-1Protein biochemistry
  • Track 2-2Organic synthesis of ligands and inhibitors
  • Track 2-3Drug metabolism
  • Track 2-4Molecular biology and genetic engineering
  • Track 2-5Ligand and structure based drug design

Track 3:Computer Aided Drug Designing

Computer-Aided Drug Design is an important journal for all medicinal chemists who wish to be kept informed and up-to-date with all the latest and important developments in computer-aided methodologies and their applications in drug discovery. Each issue contains a series of timely, in-depth reviews mini-reviews, unique research articles and letter articles written by leaders in the field, covering a range of computational techniques for drug design, broadcast, ADME studies, theoretical chemistry; computational chemistry; computer and molecular graphics; molecular modeling; protein engineering; drug design; expert systems; general structure-property relationships; molecular dynamics; chemical database development and usage etc., providing excellent rationales for drug expansion.

  • Track 3-1Computational Chemistry
  • Track 3-2Enzyme as target
  • Track 3-3Receptor as target
  • Track 3-4QSAR/QSPR Quantitative structure activity/property relationships

Track 4:Anti-Cancer agents in Medicinal Chemistry

Cancer is one of the major health hazards and the prominent cause of death in the world. A number of anticancer agent are currently in clinical practice and used for treatment of many kinds of cancers. There is no disbelief that the current resource of anticancer agents is insufficient due to the high occurrence of side effects and multidrug resistance. In the efforts to develop appropriate anticancer drugs, medicinal chemists have focused on coumrain derivatives. Coumarin is a certainly occurring compound and a versatile synthetic scaffold owning wide spectrum of biological effects including potential anticancer activity. This journal article covers the modern improvements of coumarin-based anticancer agents and also discusses the structure activity relationship of the greatest potent compounds

 

  • Track 4-1 Classification of Anti-Cancer Drugs
  • Track 4-2 Chemotherapy
  • Track 4-3 Anticancer and Anti-Diabetic Agents
  • Track 4-4 Chemotherapeutic Agents

Track 5:Bioorganic & Medicinal Chemistry

Bioorganic Chemistry goes explanations of research that are at the line of chemistry and biology. The controlling principle that the Editorial Board will follow in accepting manuscripts for publication is that the study either uses the principles and skills of organic and physical organic chemistry in struggling to solve some problem of relevance to biology or describes chemical studies that are inspired by some biological observation. Within this context, manuscripts suitable for plan are ones that deal with such matters as enzymology, enzyme models, biosynthesis and combinatorial biosynthesis, biomimetic synthesis, molecular recognition, protein and peptide chemistry, nucleic acid chemistry.

 

  • Track 5-1 Bromodomain inhibitor
  • Track 5-2 BET proteins
  • Track 5-3 Apoptosis
  • Track 5-4 Multi-target-directed ligands

 

 

Market Analysis

Market Analysis

Medicinal chemistry and Drug Discovery is a stimulating field as it links many scientific disciplines and allows for collaboration with other scientists in researching and developing new drugs. Medicinal chemists apply their chemistry training to the process of synthesizing new pharmaceuticals. They also improve the processes by which existing pharmaceuticals are made. Medicinal chemist are focused on drug discovery and development and are concerned with the isolation of medicinal agents found in plants, as well as the creation of new synthetic drug compounds.

Chemistry volumes continue to rise in the U.S. and chemical market expected to contract this year—As a result, chemical industry capital spending in the U.S. surged 12.1% in 2014 and gained 21.0% in 2015, reaching $43.58 billion and accounting for more than one-half of total construction spending by the manufacturing sector. The association representing US-based chemical producers said that US chemical production (excluding pharmaceuticals) is expected to realize the overall growth of 1.6% in 2016, followed by 4.1% growth next year, and 5.0% in 2018. Average annual gains of over 8% per year in U.S. Chemical industry capital spending are expected through 2018 with only a minor slowdown in subsequent growth expected. By 2021, ACC expects capital spending to reach $70 billion, contributing to four consecutive years of job growth in the industry. American chemistry revenues will exceed $1.0 trillion by 2020.

 

Chemistry council stated that more than 275 new chemical production projects had been announced since 2010 with a total value of more than $170 billion, with a full 49% already complete or under construction; 61% of these are the foreign direct investment. By 2021, U.S. capital spending by the chemical industry will reach $65 billion—more than triple the level of spending at the start of this prolonged cycle in 2010. The trade surplus in chemicals (excluding pharmaceuticals) will grow to $36 billion this year as exports rise by 2% to $132 billion and imports hold steady at $96 billion. Two-way trade between the U.S. and its foreign partners will reach $227 billion this year and will grow steadily over the coming years.

The popularity of Formulation and Drug Discovery has increased significantly in recent years. The Drug Delivery Technology market is expected to reach USD 1,504.7 Billion by 2020 from USD 1,048.1 Billion in 2015, growing at a CAGR of 7.5% from 2015 to 2020. Drug delivery technology market offers a promising approach for the delivery of various kinds of drugs that have different molecular formulatiom. Drug delivery technology is aimed at maximizing the drug delivery at the targeted site so as to increase the efficiency of drug and proposing improved patient

 

 

To Collaborate Scientific Professionals around the World

Conference Date August 17-18, 2020

For Sponsors & Exhibitors

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Speaker Opportunity

Past Conference Report

Supported By

Medicinal Chemistry Chemical Sciences Journal Journal of Chemistry

All accepted abstracts will be published in respective Conference Series LLC LTD International Journals.

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